However, few studies have investigated the independent and joint associations of CRF, physical activity, and sedentary time with insulin resistance in children after accounting for body fat content ( 7, 8). In addition to increased body fat content, low cardiorespiratory fitness (CRF), physical inactivity, and high levels of sedentary lifestyle have been identified as independent risk factors for insulin resistance in children ( 5, 6). Furthermore, children with a mild insulin resistance, measured by fasting plasma insulin concentration and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), have been found to be at increased risk of pre-diabetes and type 2 diabetes in adulthood ( 4). Insulin resistance during childhood may also increase the risk of atherosclerotic cardiovascular diseases in adulthood ( 3). Type 2 diabetes typically affects adults but has a long aetiology related to insulin resistance and impaired glucose regulation which are observed in overweight and obese youth ( 2). The incidence of type 2 diabetes in children and adolescents has increased during this millennium ( 1) and represents a significant health and economic burden.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |